Better drugs through crystal-gazing
Tuesday 11th May at 6:30pm
Crystals are important to the pharmaceutical sciences in two ways.
(1) If we wish to determine the structure of a molecule, a crystal acts as a clamp holding many identical molecules, thus allowing their structure to be probed with X-rays.
(2) Solid dosage forms such as tablets and capsules usually contain crystals. Results in which knowledge of molecular structure leads to an improved understanding of drug action will be presented, covering a range from novel agents against tuberculosis to biomolecules that safely enclose the essential but dangerous nutrient iron (III).
Two outstanding discoveries in which the speaker participated will be featured: the structure of boron hydrides by the Lipscomb Group (Nobel Prize 1976) and the discovery of temozolomide by the Stevens Group (sales exceeding $1 billion last year).
The lecture will conclude by relating the underlying crystal structure to the ease of compressing a drug into a solid dosage form and the solubility and bioavailability when such a dose is ingested.
This lecture is free to attend and open to all.
Tuesday 11 May at 6.30pm (tea and coffee from 6pm)
Sumpner Lecture Theatre
A buffet will follow the lecture.
Please email email@example.com
to book a seat. For further information about this event please contact Emily Watts.