Professor in Pharmaceutics/Drug Delivery
Head of Pharmacy
PG Programme Director - MSc Drug delivery/MSc Pharmaceutical Sciences
Aston Pharmacy School
School of Life and Health Sciences
Aston University
Aston Triangle
Birmingham B4 7ET
UK
email: y.perrie@aston.ac.uk
Telephone: +44 (0) 121 204 3991
Research Convener- Medicines Research Unit
Strand co-ordinator and member of research strand 'Development of novel drugs, formulations and tissues to support healthy ageing' - Aston Research Centre for Healthy Ageing
Member of the Pharmacy and Biology Teaching Programmes
Career History
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2007 - date
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Professor in Drug Delivery Aston University
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2005 - 07
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Senior Lecturer in Pharmaceutics Aston University
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2000 - 05
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Lecturer in Pharmaceutics Aston University
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1999 - 00
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Pharmaceutical Scientist/Industrial Lecturer (joint position), Lipoxen Ltd., The School of Pharmacy, University of London.
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1998 - 99
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Research Fellow, The School of Pharmacy, University of London
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1995 - 98
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PhD, The School of Pharmacy, University of London (Supervisor, Prof. G. Gregoriadis)
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1994 - 95
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Pre-registration Pharmacist training, R.W. McConnell & Son, Scotland.
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1990 - 94
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BSc Hons, Pharmacy (1st Class), University of Strathclyde
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Research Interests
- Formulation Engineering of Vaccines (including conventional and DNA vaccines)
- Enhancing solubility and delivery of bioactive molecules using colloid science and technology.
- Delivery of drugs, vaccines and gene therapies using liposomes, niosomes and other novel particulate systems
- Design, physicochemical characterisation and development of non-viral systems for gene delivery
- Tissue Engineering and regenerative medicine
- Enhancing learning methods in Pharmacy Education
Membership of Professional Bodies
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UK and Ireland Controlled Release Society (President; 2006-present)
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Controlled Release Society (Newsletter Editor; 2004 - present)
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Academy of Pharmaceutical Sciences (Board Director; 2000-2006. Newsletter Editor; 2002-2004)
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European Advisory Board for the Safe use of Adjuvants
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American Association of Pharmaceutical Scientists
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The Biochemical Society
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Industrial Pharmacists Group
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International Liposome Society
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The Royal Pharmaceutical Society of Great Britain
- WHO International Working Group on DNA Vaccines
Research Support
My research group gratefully acknowledge the support of: EPSRC, EU 6th Framework programme, Lipoxen Technologies Ltd, Pfizer Global Research, Astisen Ltd, Wellcome, and The Royal Society.
Recent Publications
PAPERS:
Malou
Henriksen-Lacey, Andrew Devitt and Yvonne
Perrie* (2011). The vesicle size of DDA:TDB liposomal adjuvants plays a
tole in the cell-mediated immune response but has no significant effect on
antibody production. J Control Release.
doi:10.1016/j.jconrel.2011.05.019
Jitinder Wilkhu,
Sarah E McNeil, Daniel J Kirby and Yvonne
Perrie. Formulation design considerations for oral vaccines. Therapeutic
Delivery. Accepted.
Farhan Alhusban,
Yvonne Perrie and Afzal UR Mohammed. (2011). Formulation of multiparticulate
systems as lyophilised orally disintegrating tablets. Euro J Pharm Biopharm.
(In press).
Behfar
Moghaddam, M Habib Ali, Jitinder Wilkhu, Daniel J Kirby, Afzal R Mohammed,
Qinguo Zheng, and Yvonne Perrie*
(2011).The application of
monolayer studies in the understanding of liposomal formulations.Int J
Pharm. (In press).
Myrra G.
Carstens, Marcel G.M. Camps, Malou Henriksen-Lacy, Kees Franken, Tom H.M.
Ottenhoff, Yvonne Perrie, Joke A.
Bouwstra, Ferry Ossendorp, Wim Jiskoot (2011). Effect of vesicle size on tissue
localization and immunogenicity of liposomal DNA vaccines. Vaccine
29(29-30):4761-70.
Sheraz Khan,
Hannah Batchelor, Peter Hanson, Yvonne
Perrie, and Afzal R Mohammed(2011). Physicochemical characterisation, drug
polymer dissolution and in vitro evaluation of phenacetin and phenylbutazone
solid dispersions with polyethylene glycol 8000. Journal of Pharmaceutical
Sciences (In press).
Malou
Henriksen-Lacey, Karen Smith Korsholm, Yvonne
Perrie, Peter Andersen, Dennis Christensen
(2011). System Liposomal Vaccine Delivery systems. Expert opin Drug Deliv.
8(4):505-519.
Randip
Kaur, Jili Chen, Amina Dawoodji,
Vincenzo Cerundolo, Yoel R. Garcia-Diaz, Justyna Wojno, Liam R. Cox, Gurdyal S
Besra, Behfar Moghaddam, Yvonne Perrie
(2011). Preparation, characterisation and entrapment of a non-glycosidic
threitol ceramide into liposomes for presentation to invariant natural killer T
cells. J Pharm Sci. 100(7):2724-33.
Sarah McNeil,
Helen R Griffiths and Yvonne Perrie
(2011). Polycaprolactone fibres as a
potential delivery system for collagen to support bone regeneration. Curr
Drug Deliv. [In press]
Sheraz Khan, Amr
ElShaer , Ayesha S Rahman, Peter Hanson, Yvonne
Perrie, and Afzal R Mohammed (2011). Systemic biology approach to study permeability of paracetamol and its
solid dispersion. Int J Pharm.
2010 Dec 25. [In press]
Sagida Bibi,
Randip Kaur, Malou Henriksen-Lacey, Sarah E. McNeil, Jitinder Wilkhu, Eric
Lattmann, Dennis Christensen, Afzal
R Mohammed and Yvonne Perrie*
(2011). Microscope imaging of liposomes: From coverslips to environmental SEM. Int J Pharm. 2010 Dec 21. [In press]
Sarah McNeil,
Ida Rosenkrands, Else Marie Agger, Peter Andersen and Yvonne Perrie (2011). Subunit vaccines:
Distearoylphosphatidylcholine based liposomes entrapping antigen offer a
neutral alternative to dimethyldioctadecylammonium
based cationic liposomes as an adjuvant delivery system. J
Pharm Sci. 100(5)1856-65.
Malou
Henriksen-Lacey, Dennis Christensen, Vincent W. Bramwell, Thomas Lindenstrøm,
Else-Marie Agger, Peter Andersen, Yvonne
Perrie (2011). Comparison of the depot effect and immunogenicity of
liposomes based on DDA, DC-Chol and DOTAP: Prolonged liposome retention
mediates stronger Th1 responses. Molecular Pharmaceutics. Mol
Pharm. 8(1):153-61.
Khan S, Elshaer
A, Rahman AS, Hanson P, Perrie Y,
Mohammed AR (2010). Genomic evaluation during permeability of indomethacin and
its solid dispersion. J Drug Target.
2010 Nov 16. [Epub ahead of print]
Nooshin
Daneshpour, Martin Griffin, Russell Collighan and Yvonne Perrie. (2010) Targeted delivery of a novel group of site
directed transglutaminase inhibitors to the liver using liposomes: a new
approach for the potential treatment of liver fibrosis. J Drug
Target. 2010 Nov 11. [Epub ahead of print]
Ali, M.H., Kirby, DJ, Mohammed AR, Perrie Y (2010). Solubilisation of drugs within liposomal bilayers – alternatives to
cholesterol as a membrane stabilising agent. J Pharm Pharmacol. 62 (11):
1646-1655.
Afzal R
Mohammed, Vincent W Bramwell, Daniel Kirby, Sarah E McNeil and Yvonne Perrie (2010). Increased
Potential of a Cationic Liposome Based Delivery System: Enhancing Stability and
Sustained Immunological Activity in Pre-Clinical Development. Eur
J Pharm Biopharm. 2010 Nov;76(3):404-12.
Deepa Mohanan,
Malou Henriksen-Lacey, Bram Slütter, Wim Jiskoot, Joke Bouwstra , Yvonne Perrie, Thomas M. Kündig Bruno
Gander, and PålJohansen (2010). Administration routes affect the
quality of immune responses: a cross-sectional evaluation of particulate
antigen-delivery systems. J Control Release. 147(3), 342-249.
Malou
Henriksen-Lacey, Dennis Christensen,
Vincent W. Bramwell, Thomas Lindenstrøm, Else-Marie Agger, Peter Andersen, Yvonne Perrie (2010). Liposomal
cationic charge and antigen adsorption are important properties for the
efficient deposition of antigen at the injection site and immunogenicity of the
vaccine. J Control Release. 145; 102-108.
Malou
Henriksen-Lacey, Vincent W. Bramwell and Yvonne
Perrie (2010). Radiolabelling of Antigen and Liposomes for Vaccine
Biodistribution Studies. Pharmaceutics, 2, 91-104;
doi:10.3390/pharmaceutics2020091.
Farhan AlHusban,
Yvonne Perrie and Afzal R Mohammed
(2010). Formulation and characterisation of lyophilised rapid disintegrating
tablets using amino acids as matrix forming agents. Eur J
Pharm Biopharm. 75(2), 254-262.
McNeil SE,
Vangala, A, Bramwell, VW, Hanson, PJ and Perrie,
Y (2010). Lipoplexes formulation and optimisation: In vitro transfection
studies reveal no correlation with in vivo vaccination studies. Current Drug
Delivery. 7, 175-187.
Chang, H-I.,
Wang, Y., Perrie, Y. and Coombes,
A.G.A (2010). Microporous polycaprolactone matrices for drug delivery and
tissue engineering: the release behavior of bioactive having extremes of
aqueous solubility. J Drug Del Sci
Tech., 20(3) 207-212.
Smith AM, Ingham
A, Grover LM and Perrie Y (2010).
Polymer film formulations for the preparation of enteric pharmaceutical
capsules. J Pharm Pharmacol. 62 (2): 167-172.
Malou
Henriksen-Lacey, Vincent W. Bramwell, Dennis Christensen, Else-Marie Agger,
Peter Andersen, Yvonne Perrie
(2010). Liposomes based on dimethyldioctadecylammonium promote a depot effect
and enhance immunogenicity of soluble antigen. J Control Release. 142 (2)
180-186.
Perrie Y, Ali H, Kirby
DJ, Mohammed AU, McNeil SE, Vangala A (2010). Environmental scanning electron
microscope imaging of vesicles. Methods Mol Biol; 606:319-331.
Farahan Al
Husban, Amr M. ElShaer, Jiteen H. Kansara, Alan M. Smith, Liam M. Grover, Yvonne Perrie and Afzal R. Mohammed
(2010). Investigation of Formulation and Process of Lyophilised Orally
Disintegrating Tablet (ODT) Using Novel Amino Acid Combination. Pharmaceutics.
2(1), 1-17. http://www.mdpi.com/1999-4923/2/1/1/pdf
Alhusban F, Perrie Y, Mohammed AR (2010).
Preparation, Optimisation and Characterisation of Lyophilised Rapid
Disintegrating Tablets Based on Gelatin and Saccharide. Curr Drug Deliv. 7,
65-75.
R Kaur, R
Morris, M Bencsik, A Vangala, T Rades, Y
Perrie (2009) Development of a novel magnetic resonance imaging contrast
agent for pressure measurements using lipid-coated microbubbles. J Biomed
Nanotechnol. 5 (6), 1-9.
Christensen D,
Agger EM, Andreasen LV, Kirby, DJ, Andersen P, Perrie Y (2009). Liposome-based cationic adjuvant formulations
(CAF): Past, present, and future. J Liposome Res. 19(1) 2-11.
Bhowruth V,
Minnikin DE, Agger EM, Andersen P, Bramwell VW, Perrie Y, Besra GS (2009) Adjuvant properties of a simplified C32
monomycolyl glycerol analogue. Bioorg Med Chem Lett. 2009 19(7) 2029-32.
Hofmann, MP, Mohammed AR, Perrie Y, Gbureck U, Barralet JE* (2009)
High Strength brushite bone cement with controlled drug releasing capabilities.
Acta Biomater 5(1):43-49. (IF 3.1).
Perrie, Y*, Mohammed, A.R., Kirby, D.J., McNeil, S.E. and
Bramwell, V.W. (2008) Vaccine adjuvant systems: enhancing the efficacy of
sub-unit protein antigens. Int. J Pharm. 364 272-280
Clark, S., Cross, L M., Smith, A.M., Court, P., Vipond J, Nadian, A.,
Hewinson R.G., Batchelor H, K.,
Perrie, Y., Williams, A.,
Aldwell, F.E. &. Chambers, M.A. (2008) Assessment of different formulations
of oral Mycobacterium bovis Bacille Calmette-Guerin (BCG) vaccine in rodent
models for immunogenicity and protection against aerosol challenge with M Bovis. Vaccine. 26(46): 5791-7
Perrie,
Y*.
(2008). Gregory Gregoriadis: Introducing liposomes to drug delivery. J Drug
Target. 16(7):518-9.
Kirby, DJ,
Rosenkrands, I., Agger, E-M. Andersen, P., Coombes AGA., and Perrie, Y* (2008). Liposomes act as
stronger sub-unit vaccine adjuvants when compared to microspheres. J. Drug
Target, 16(7):543-54.
Robert H Morris, Martin
Bencsik, Nikolaus Nestlé, Petrik Galvosas, David Fairhurst, Anil Vangala, Yvonne Perrie, Glen McHale (2008). Robust spatially resolved
pressure measurements using MRI with novel buoyant-advection free preparations
of stable microbubbles in polysaccharide gels. J Magn Reson;
193(2) :159-67.
Christensen
D, Kirby D, Foget C, Agger EM, Andersen P, Perrie
Y, Nielsen HM (2008). alpha,alpha'-trehalose 6,6'-dibehenate in non-phospholipid-based
liposomes enables direct interaction with trehalose, offering stability during
freeze-drying.Biochim Biophys Acta. 2008; 1778(5):1365-1373.
Kirby, DJ, Rosenkrands, I., Agger, E-M. Andersen,
P., Coombes AGA., and Perrie, Y*
(2008). PLGA microspheres for the delivery of a novel subunit TB vaccine J.
Drug Target, 2008; 16(4) 282-293.
Vangala, AK, R.H.Morris, RH, Bencsik, M, and Perrie, Y* (2007). Preparation and
characterization of gas-filled liposomes: Can they improve oil recovery. J Liposome
Res., 17(3):263-272.
Smith, AM.,
Shelton, RM Perrie, Y and Harris,
JJ* (2007). An initial evaluation of gellan gum as a material for tissue
engineering applications. J Biomater Appl, 2007. 22(3); 241-254. doi:10.1177/0885328207076522
*Perrie, Y., Mohammed,
A.R., Vangala, A., and McNeil, S.E (2007). Environmental Scanning Electron
Microscopy Studies of Liposomes and Niosomes, J Liposome Res. 17(1): 27-37.
*Perrie, Y., Kirby, DJ.,
Bramwell, V.W. and Mohammed, A.R (2007). Recent developments in particulate
vaccines. Recent Patents on Drug Delivery & Formulation. 1, 117-129.
R.H.Morris, RH*,
Vangala, AK, Bencsik, M, Perrie, Y (2007)
Three dimensional fluid pressure mapping in porous media using magnetic
resonance imaging with gas filled liposomes. Mag. Res. Imaging, 2007, 25(4)
509-512.
Smith, AM.,
Harris, JJ, Shelton, RM and Perrie, Y*.
(2007) 3D culture of bone-derived cells immobilized in alginate following
light-triggered gelation. J. Control. Release.
94-101.
Vangala, A.,
Bramwell, V.W., McNeil, E, Christensen, D., Agger, E-M., and Perrie, Y*. (2007) Comparison of
vesicle based antigen delivery systems for delivery of hepatitis B surface
antigen. J. Control. Release. 119(1):102-110.
Mohammed, AR.,
Coombes, AGA., and *Perrie, Y (2007)
Amino Acids as Cryoprotectants for Liposomal delivery systems. Euro J Pharm
Sci, 406-413.
Mohammed, A.R.,
Bramwell, V.W., Coombes, A.G.A., *Perrie,
Y (2006). Lyophilisation and sterilisation of liposomal vaccines to produce
stable and sterile products. Methods, 40: 30-38.
Vangala. A.K., Kirby, D., Rosenkrands, I., Agger, E-M., Andersen, P.
and. *Perrie, Y (2006) A comparative study of cationic liposomes and
niosome-based adjuvant systems for protein subunit vaccines: Characterisation,
Environmental Scanning Electron Microscopy analysis and immunisation studies. J. Pharm Pharmacol, 58:787-799.
Bramwell V.W. & Perrie,
Y* (2006). Particulate delivery
systems for vaccines: What can we expect? J. Pharm Pharmacol, 58:717-28.
McNeil, S.E. and
*Perrie, Y (2006). Gene Delivery
using cationic lipids. Expert Opinion in Therapeutic Patents. 16(10):1371-1382.
Chang, H-I., Perrie, Y. and
*Coombes, A.G.A (2006). Delivery of the antibiotic gentamicin sulphate from
precipitation cast matrices of polycaprolactone. J. Control. Release, 110:414-421
Gorst,
N.J.S., Perrie, Y., Gbureck, U.,
Hutton, A.L., Hofmann, M.P., Grover L.M., and Barralet J.E (2006). Effect of fibre
reinforcement on the mechanical properties of brushite cement. Acta Biomater, 2(1):95-102.
Davidsen, J., Rosenkrands,
I., Christensen, D., Vangala, A., Kirby, D., Perrie, Y., Agger, E-M., *Andersen, P (2005). Characterization of
cationic liposomes based on dimethyl dioctadecyl ammonium and synthetic cord
factor from M. tuberculosis (trehalose 6,6‘-dibehenate) - a novel adjuvant
inducing both strong CMI and antibody responses. Biochim Biophys Acta, 1718,
22-31.
Bramwell, V.W.
& *Perrie, Y (2005) The rational
design of vaccines. Drug Discov Today, 2005, 10 (22) 1527-1534.
Chang, H-I., Williamson, M.R., Perrie,
Y. and *Coombes, A.G.A. Precipitation casting of Drug-loaded microporous
PCL Matrices: Incorporation of Progesterone by co-dissolution. J. Control. Release, 2005, 106,(3): 263-272.
Bramwell, V.W. & *Perrie, Y (2005). Particulate delivery systems
for vaccines. Crit Rev Ther Drug Carrier Syst, 2005, 22(2):151-214.
Mohammed, A.R., Coombes, A.G.A, Fitzgerald, M., and *Perrie, Y
(2004) Liposome formulation of poorly water soluble drugs: Optimisation of drug
loading and ESEM analysis of stability.Int. J. Pharm, 285, 23-34.
*Perrie, Y., Barralet, J.E., McNeil, S. and Vangala. A.K
(2004) Liposome and niosome mediated DNA vaccination via the subcutaneous
route. Int. J. Pharm, 284, 31-41.
*Perrie, Y., McNeil, S. and Vangala. A.K (2003).
Liposome-mediated DNA immunisation via the subcutaneous route. J. Drug Targeting, 11, 555-563.
Perrie, Y. Obrenovic, M, McCarthy, D. and Gregoriadis, G
(2002). Liposome-mediated DNA vaccination via the oral route. J Liposome Res, 12,185-197
Perrie, Y., Frederik P.M., and Gregoriadis, G (2001).
Liposome-mediated immunisation: The effect of vesicle composition.Vaccine, 19,
3301-3310
Perrie, Y. and Gregoriadis, G (2000). Liposome-entrapped
plasmid DNA: Characterisation Studies. Biochim Biophys Acta, 1475,125-132.
Gregoriadis, G., McCormack, B., Obrenovic, M., Saffie, R., Zadi, B. and Perrie,
Y (1999). Vaccine entrapment in Liposomes. Methods, 19,156-162.
EDITORIALS
Rades T and Perrie Y (2011). Advanced characterisation techniques.
International Journal of Pharmaceutics. In press.
Perrie Y and Rades T (2010). Themed Issue. Improve dissolution, solubility and
bioavailability of poorly soluble drugs. J Pharm Pharmacol. 62(11):1517-8
Perrie Y. (2009). Liposomes, lipid
assemblies, nanotechnology, and everything interesting in between. J liposome
Res (Editorial). 19(1):1
Perrie Y and Mohammed AR (2009).
Pharmaceutics: A New Open-access journal for all those interested in designing
medicines. 1(1), 1-2.
JOURNALS - (PROFESSIONAL - OTHER):
Perrie, Y*, Smith, AM.,
Harris, JJ, and Shelton, RM (2006).
A new trick for an old delivery system. Pharm J. 277: 780.
Perrie, Y. Influenza
symptoms and treatments. Pharm J. 2006, 277: 399:402.
Perrie, Y. Vaccines: an
overview and update. Pharm J. 2006. 276(7388): 209-212.
Perrie, Y (2005) How
Pharmaceutical Scientists are going prospecting for black gold. Pharm J. 275(1): 809.
PUBLISHED ARTICLES (EDUCATION):
Perrie, Y. Optimisation of assessment and feedback in large-group practicals. J Pharm Pharmacol. 2004, 56, S-63.
Perrie, Y. Turning a dull lecture into an unforgettable learning experience. Pharm. J. 2003a, 270, 754-6.
Perrie, Y. Virtual Learning Environments. Pharm.
J. 2003b, 270, 794-5.
Perrie, Y. Choosing an Assessment Strategy. Pharm. J. 2003c, 271,
86-88.
Wittingham, C and Perrie, Y.
(2002). Application of “Exocharmic” Demonstrations in Pharmaceutics Lectures. Pharmacy Education, 2002, 2,157-8.
PATENTS:
Anderson D, Wilku J, Perrie Y. Lipid Vaccine formulations. U.S. provisional patent
application Serial Number 61/432,569 was filed with the United States Patent
and Trademark Office (USPTO) on January 13, 2011.
Mohammed AUR, Alhusban F, Perrie Y. Orally disintegrating tablets. UK
Patent Application No 0920041.1.
Smith, AM. & Perrie Y.
Enteric Pharmaceutical Capsules. Filed 26/03/08 GB/29.3.07/GBA 0706178. PCT/GB2008001038
Perrie, Y. Griffiths, H.R., Phillips, D.C. Ceramide
derivatives for the treatment of inflammation. 2004. Patent number
W02004064823. (Published 05/08/2004)
Gregoriadis, G. and Perrie, Y. Liposome-entrapped DNA oral
vaccines. 2001 Patent
number WO0124773, (Published 12/04/2001)
REVIEWS (INVITED):
Bramwell, V.W. & Perrie, Y (2007). Natural and synthetic
additives. European Biopharmaceutical Review. Spring: 78-83.
Perrie, Y (2005) Liposome delivery of sparingly soluble drugs. European Biopharmaceutical Review. Autumn:
90-97.
Mohammed, A.R. & *Perrie, Y.
(2005) Liposome solutions for sparingly soluble drugs. Drug Delivery Companies
Report. Autumn/Winter, 2005, 9-11.
BOOK CHAPTERS:
Perrie Y (2010).
Vaccines for a new era. In The new optimists: scientists view tomorrow’s world
& what it means to us. Linus Publishing.
Gregoriadis G,
and Perrie Y. (2010). Liposomes. In
Encyclopaedia of Life Sciences. John Wiley & Sons, UK.
ChristensenD, KorsholmK, WoodKJ, Mohammed AM, Bramwell VW,
Agger EM and Perrie Y (2009).
Liposomes as adjuvant systems for parenteral delivery of vaccines. In Delivery
Technologies for Biopharmaceuticals: Peptides, Proteins, Nucleic Acids and
Vaccines.
Gregoriadis, G.,
McCormack, B., Perrie, Y., Bacon, A., Caparros-Wanderley, W. and Zadi,
B.(2003). Liposome-based DNA vaccines: Procedures for entrapment. In Liposomes
- A practical approach, 2nd ed., V.P. Torchilin, and V. Weissig eds. Oxford
University Press. Practical Approach Series.
Perrie, Y. and Gregoriadis, G. (2000) Liposomal DNA Vaccines: Structural
Characteristics. In Gregoriadis and McCormack, (Ed.) Targeting of Drugs, Targeting of Drugs: Strategies for Gene Constructs
and Delivery. p. 102-111, Amsterdam, The Netherlands: IOS Press.
Gregoriadis, G.,
McCormack, B., Obrenovic, M., Perrie, Y. and Yang, J-C. (2000) Genetic
Vaccines: A Role for Liposomes. In Gregoriadis and McCormack, (Ed.) Targeting of Drugs, Targeting of Drugs:
Strategies for Gene Constructs and Delivery, p. 92-110. Amsterdam, The
Netherlands: IOS Press.
Gregoriadis, G.,
McCormack, B., Obrenovic, M., Perrie, Y. and Saffie, R. (2000)
Liposomes As Immunological Adjuvants and Vaccine Carriers. In O'Hagen D.T.
(Ed). Methods in Molecular Medicine,
vol 42, Vaccine Adjuvants: Preparation Methods and Research Protocols.
p. 137-150. Totowa, NJ: Humana Press Inc.
Gregoriadis, G.,
McCormack, B., Obrenovic, M., and Perrie, Y. (1999) Entrapment of
Plasmid DNA Vaccines into Liposomes by Dehydration/Rehydration. In Lowrie, D.B.
and Whalen, R. (Eds.) Methods in
Molecular Medicine, vol 9, DNA Vaccines: Methods and Protocols. p.
305-312. Totowa, NJ: Humana Press Inc.
Gregoriadis, G.,
McCormack, B., Morrison (Perrie), Y., Saffie, R. and Zadi, B. (1998)
Liposomes in drug targeting. In: Cellis, J.E. (Ed.) Cell biology: A laboratory handbook, 2nd edn. p. 131-140. New
York: Academic Press.
Gregoriadis, G.,
McCormack, B., Perrie, Y. and Saffie, R. (1998) DNA Vaccination: A role
for liposomes. In: Lasic, D.D. and Papahadjopoulos, D. (Eds.) Medical applications of liposomes, p.
61-73. New York: Elsevier Science.
Gregoriadis, G.,
McCormack, B., Perrie, Y. and Saffie, R. (1998) Liposome-mediated DNA
vaccination. In: Janoff, A. (Ed.) Liposomes:
Rational Design, p. 205-218. New York: Marcel Dekker, Inc.
BOOKS: