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Dr Lindsay J Marshall

Dr Lindsay J Marshall profile

Lecturer in Immunology

School of Life and Health Sciences
Aston University
Aston Triangle
Birmingham B4 7ET
UK

email: l.marshall@aston.ac.uk
telephone: +44 (0) 121 204 4017
fax: +44 (0) 121 204 3892

Member of the Molecular Biosciences Research Group 
Member of research strand 'Mechanisms of age-related transitions' - Aston Research Centre for Healthy Ageing

Member of the Pharmacy and Biology Teaching Programmes

Teaching Activity on the MPharm Programme

PH2502: Immunology teaching

Career History

2004-date Lecturer in Immunology, Aston University

2001-2004 Research Fellow, Portsmouth University

1998-2000 Research Fellow, Southampton University

1994-1998 PhD Cell Biology, University of Dundee

1993 MSc Experimental and Molecular Pathology, University of Dundee

1988-1992 BSc (Hons) Biology, University of Stirling

Research Interests

  • Mucosal immunology
  • Modelling the airways epithelium in vitro
  • Protein glycosylation in health and disease
  • Host-pathogen and pathogen-pathogen interactions

Recent Publications

  • Marshall, L.J., Perks, B., Bodey, K., Suri, R., Bush, A., and Shute, J. K. (2004) Free secretory component from cystic fibrosis sputa displays the CF glycosylation phenotype. Am. J. Respir. Crit Care Med. 169:3; 399-406.
  • Marshall, L.J., Ramdin, L.S.P., Brooks, T, Charlton, P., Shute, J.K. (2003) Plasminogen activator inhibitor-1 supports interleukin-8–mediated neutrophil transendothelial migration by inhibition of the constitutive shedding of endothelial IL-8/heparan sulphate/syndecan-1 complexes. J Immunol. 171:2057-2065.
  • J. K. Shute, L. J. Marshall, K. Bodey and A. Bush. (2003) Growth factors in cystic fibrosis: when more is not enough. Paediatr Respir Rev. 4(2):120-7.
  • R. Suri, L. J. Marshall, C. Wallis, C. Metcalfe, J. K. Shute and A. Bush (2003) Safety and use of sputum induction in children with cystic fibrosis. Pediatr Pulmonol. 2003. 35(4):309-13.
  • R. Suri, L. J. Marshall, C. Wallis, C. Metcalfe, A. Bush and J. K. Shute. (2002) Effects of recombinant human DNase and hypertonic saline on airway inflammation in children with cystic fibrosis. Am. J. Respir. Crit. Care Med. 166(3):352-5.
  • Marshall, L.J., Perks, B. Ferkol, T., and Shute, J.K. (2001) Interleukin-8 released constitutively by primary bronchial epithelial cells in culture forms an inactive complex with secretory component. J Immunol. 167:2816-2823.
  • Treharne K.J., Riemen C.E., Marshall L.J., Muimo R., Mehta A. (2001) Nucleoside diphosphate kinase--a component of the [Na(+)]- and [Cl(-)]-sensitive phosphorylation cascade in human and murine airway epithelium. Pflugers Arch. 443 Suppl 1:S97-102.
  • Marshall, L.J., Muimo, R., Reimen, C. E. and Mehta, A. (1999) Na+ and K+ regulate the phosphorylation state of nucleoside diphosphate kinase in human airway epithelium. Am J Physiol 276 (Cell Physiol 45): C109-C119.
  • Muimo, R., Banner, S.J., Marshall, L.J. and Mehta, A. (1998) Nucleoside diphosphate kinase and Cl- sensitive protein phosphorylation in apical membranes from ovine airway epithelium. Am J Respir Cell Mol Biol 18:2: 270-278.
  • Treharne, K.J., Marshall, L.J. and Mehta, A. (1994) A novel, chloride-dependent, GTP-utilising kinase in plasma membranes from human respiratory epithelium. Am J Physiol (Lung Cell Mol Biology) 267: L592-L601.