Professor Ian Holliday BSc PhD DIC

Career History

Graduated in Physics from Imperial College, University of London, from where he also obtained his PhD.

Current Research Interests

Human psychophysics and brain imaging

My main research work has focussed on human vision, both normal and abnormal, using psychophysical methods, MEG and fMRI. Some research interests are:

• MEG investigations of pattern processing, aiming to tease apart the contributions from each region of the brain, from the earliest responses to simple features of objects to the complex interactions needed to perceive whole objects and perform complex tasks such as reading.
• Motion perception has been a long-term interest, and was the area I first worked in as a research student using psychophysical methods. More recently I have used MEG and fMRI to study the brain regions responding to moving patterns and objects.
• Using computer simulations to find out how the signals measured using MEG result from the combined action of millions of brain cells, and how these link to what we see.
• The application of MEG to clinical conditions such as migraine, Amblyopia, and epilepsy, and other patient groups.

Teaching Responsibilities

Administrative Role

Member of the Human Sciences Ethical Committee (Psychology)

Publications

Fisher AE, Barnes GR, Hillebrand A, Holliday IE, Witton C, Richards IL. (2006). Abnormality of mismatch negativity in response to tone omission in dyslexic adults. Brain Res. Mar 10;1077(1):90-8.

Hadjipapas A, Hillebrand A, Holliday IE, Singh KD, Barnes GR. (2005). Assessing interactions of linear and nonlinear neuronal sources using MEG beamformers: a proof of concept. Clin Neurophysiol. Jun;116(6):1300-13.�
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Hall SD, Holliday IE, Hillebrand A, Furlong PL, Singh KD, Barnes GR. (2005). Distinct contrast response functions in striate and extra-striate regions of visual cortex revealed with magnetoencephalography (MEG). Clin Neurophysiol. Jul;116(7):1716-22.

Hall SD, Holliday IE, Hillebrand A, Singh KD, Furlong PL, Hadjipapas A, Barnes GR. (2005). The missing link: analogous human and primate cortical gamma oscillations. Neuroimage. May 15;26(1):13-7.
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Hillebrand A, Singh KD, Holliday IE, Furlong PL, Barnes GR. (2005). A new approach to neuroimaging with magnetoencephalography. Hum Brain Mapp. Jun;25(2):199-211. Review.
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Holliday IE, Meese TS. (2005). Neuromagnetic evoked responses to complex motions are greatest for expansion. Int J Psychophysiol. Feb;55(2):145-57.

Fisher AE, Barnes GR, Hillebrand A, Burrow C, Furlong PL, Holliday IE. (2004). Can you tell your clunis from your cubitus? A benchmark for functional imaging. BMJ. Dec 18;329(7480):1492-3.

Adjamian P, Holliday IE, Barnes GR, Hillebrand A, Hadjipapas A, Singh KD. (2004). Induced visual illusions and gamma oscillations in human primary visual cortex. Eur J Neurosci. Jul;20(2):587-92.

Adjamian P, Barnes GR, Hillebrand A, Holliday IE, Singh KD, Furlong PL, Harrington E, Barclay CW, Route PJ. (2004). Co-registration of magnetoencephalography with magnetic resonance imaging using bite-bar-based fiducials and surface-matching. Clin Neurophysiol. Mar;115(3):691-8.

Hall SD, Barnes GR, Hillebrand A, Furlong PL, Singh KD, Holliday IE. (2004). Spatio-temporal imaging of cortical desynchronization in migraine visual aura: a magnetoencephalography case study. Headache. Mar;44(3):204-8.

Holliday IE, Barnes GR, Hillebrand A, Singh KD. (2003). Accuracy and applications of group MEG studies using cortical source locations estimated from participants' scalp surfaces. Hum Brain Mapp. Nov;20(3):142-7.