Pharmacy
Profile
I joined Aston Pharmacy School in January 2011 having spent three years as a research fellow at the School of Pharmacy, Queens University Belfast, working in the area of mucosal drug delivery to the vagina for the prevention of HIV. I worked as part of a worldwide multi-disciplinary team. I have experience in formulation of many delivery systems, and in pharmacokinetic and pharmacodynamic studies.
Teaching Activity on the MPharm Programme
PH3603: Pharmaceutical formulation
PH4701: Clinical pharmaceutics and drug delivery
Qualifications & Education
- MPhil in Orthopaedic and Trauma, Queens University Belfast
- PhD in Pharmaceutics, Queens University Belfast
Employment
- 2011 – present: Lecturer in Pharmaceutics, Aston Pharmacy School, Aston University.
- 2007 – 2010: Research Fellow, School of Pharmacy, Queens University Belfast
Teaching activity
I teach 3rd year MPharm Pharmaceutics module PH3CT1 (Modified release) and MSc Drug Delivery and Design module PHM010. I am the module co-ordinator for PHM010.
Research interests
- Member of the Medicines Research Group
- Design of modified release systems for controlled delivery of peptides, proteins and vaccines.
- Mucosal drug delivery
- Aquasomes for vaccine delivery
- Polymeric delivery systems
- Pulmonary delivery
PhD Supervision
Opportunities are available for prospective, self-funded MPhil and PhD level research students to conduct research in the area of controlled release.
Collaborative research is welcomed.
Membership of Professional Bodies
- Royal Pharmaceutical Society
- Fellow of the Higher Education Academy
- Academy of Pharmaceutical Sciences
- Controlled Release Society
- UK and Ireland Controlled Release Society
Selected publications
Papers
Non-aqueous silicone elastomer gel as a vaginal microbicide delivery system for the HIV-1 entry inhibitor maraviroc, C.J. Forbes, D. Lowry, L. Geer, R.S. Veazey, R.J. Shattock, P.J. Klasse, M. Mitchnick, L. Goldman, L.A. Doyle, B.C.O. Muldoon, A. David Woolfson, J.P. Moore, R. Karl Malcolm. Journal of Controlled Release, 2011: 156 (2) 161-169
Potential use of vaginal rings for prevention of heterosexual transmission of HIV, A.D.Woolfson, R.K Malcolm, C. Toner, R. Morrow, D. Lowry, A. Jamil, S.D. McCullagh. American journal of drug delivery,2006; 4(1) 7-20
Vaginal microbicides for the prevention of HIV transmission, R.K. Malcolm, A.D Woolfson, C. Toner, D. Lowry, Biotechnology and genetic engineering reviews, 2004; 21: 81-121
Conference abstracts
Pre-treatment with Depo-Provera modifies the pharmacokinetics of CMPD167 in rhesus macaques following vaginal ring administration. R.K.Malcolm, D. Lowry, L. Freen, R. Shattock, M. Mitchnick, L. Geer, P. Klasse, J. Moore, R. Veazey, Microbicides Conference 2010, Pittsburgh, USA
Non-aqueous silicone elastomer gels for practical formulation of water soluble and insoluble HIV microbicides. D. Lowry, C. Forbes, C. McConville, A.D.Woolfson, R.K. Malcolm, Controlled Release Society Conference 2010, Portland, USA
Development of a microbicide-releasing SILCS diaphragm. I. Major, D. Lowry, K. Malcolm, D. Woolfson, J. Cohen, P. LaBarre. Controlled Release Society Conference 2010, Portland, USA
Silicone elastomer rings for sustained delivery of HIV microbicides : correlating historical in vitro and in vivo release data. D. Lowry, S. Fetherston, C, McConville, A.D. Woolfson, R.K. Malcolm, Microbicides Conference 2010, Pittsburgh, USA
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