2009 - Community Pathways CIC
Director
2008 - Awarded the Aston Excellence Award for an outstanding contribution to Community Engagement
2006 - 2007 University of Leicester
Postgraduate Certificate in Higher Education Leadership (Distinction)
2005 - 2008 Aston University, LHS
Business Development Manager
2004 - 2005 Aston University
MEDICI Fellowship
2003 - 2005 OU Lecturer
Taught UG Level 3 Molecular & Cell Biology by DL
2003 - 2004 Aston University, LHS
Lecturer in Cell & Molecular Biology
2001 - 2003 University of Keele, Staffordshire
Lecturer in Parasitology/Cell Biology
1998 - 2001 University of Wolverhampton
Research Assistant/PhD Molecular Pharmacology
Lectured in Medical Parasitology
1995 - 1998 University of Leicester
Researcher in the Department of Genetics
1994 - 1995 University of Leicester
MSc. Molecular Genetics
Patented an idea for a Malaria Diagnostic Test
Awarded The Amersham Prize - for Innovation and Persistence
1993 - 1994 Vale of Catmose College, Oakham, Rutland
Teacher of Science
1992 - 1993 Keele University, Staffordshire
Demonstrator and Researcher, published results of Final Year project
1988 -1992 Keele University, Staffordshire
BSc. 2:1 (Hons)
Principal degree subjects: Biology and Psychology.
Subsidiary subjects: Chemistry and Russian Studies.
Concurrent Certificate in Education, Secondary Education Teacher of Science (DES reference number RP91/36203)
Recent funding
Food Safety Training £57K
A joint grant with Birmingham City Council from the
Food Standards Agency to deliver a project called Safer Food Better
Business for Asian Caterers; 180 businesses trained = 749 staff members
including many staff who are unable to speak English. I was actively
involved in this project which meant going into the community and
recruiting Asian caterers face-to-face for training.
Lifelong Learning Network Grant £85K
A team of experts in Microbiology from Aston University
will visit 9 schools in 3 years spending 2 days working with young
people in the 13-16 age group. The team will pass on their knowledge of
the invisible world of microorganisms, making the invisible become
visible with the use of microscopes and TV lenses and other devices.
Young people will learn all about microorganisms; how they grow; how
they spread; the disease states that they cause; how to treat
infections and how to prevent infections from occurring. We will visit
3 schools a year for 3 years and the schools will be chosen in
collaboration with Heart of Birmingham teaching Primary Care Trust, one
of our partners from the Midlands Health Academy.
PhD Supervision
My PhD student. Vijay D’Souza, successfully completed
his PhD in December 2007 and is currently working as a Post-Doc at
Birmingham University.
Publications
Kearns, J. Y. and
Hurd, H. (1993) Circulatory and storage carbohydrates in Hymenolepis
diminuta infected Tenebrio molitor. (Poster at the British Society for
Parasitology Spring Meeting).
Kearns, J. Y., Hurd, H. and Pullin, A.S. (1994) The
effect of the metacestodes of the rat tapeworm Hymenoleps diminuta on
circulating and storage carbohydrates in the intermediate host Tenebrio
molitor. Parasitology, 108, 473-478.
British Patent Application No. M96/0111/GB (1996) Malaria Diagnostic Test.
Inventors Dr. Michael Murray and Julia Brown.
Gibson, W., Winters, K., Mizen, G., Kearns. J. and
Bailey, M. (1997) Intraclonal mating in Trypanosoma brucei is
associated with outcrossing. Microbiology, 143, 909-920.
Gibson W., Crowe, M., and Kearns, J. (1997)
Kinetoplast DNA minicircles are inherited from both parents in genetic
crosses of Trypanosoma brucei. Parasitology Research. 83, 483-488.
Brown, J., Dubrova, Y., Plumb, M. Bois, P. and
Jeffreys, A. J. (1997) Radiation sensitivity in male mouse germ cells.
Talk at the Wellcome Trust Mammalian Genetics and Development Workshop.
Dubrova, Y. E., Plumb, M., Brown, J., Fennelly, J.,
Bois, P., Goodhead, D. and Jeffreys, A. J. (1998) Stage specificity,
dose response, and doubling dose for mouse minisatellite mutation
induction by acute radiation. Proceedings of the National Academy of
Sciences, USA. 95, 6251-6255.
Bois, P., Williamson, J., Brown, J., Dubrova, Y.
and Jeffreys, A. J. (1998) A novel unstable mouse VNTR family expanded
from SINE B1 elements. Genomics, 49, 122-128.
Dubrova, Y. E., Plumb, M., Brown, J. and Jeffreys,
A. J. (1998) Radiation-induced germline instability at minisatellite
loci. International Journal of Radiation Biology. 74, 689-696.
Dubrova, Y. E., Plumb, M., Brown, J. and Jeffreys,
A. J. (1999) Radiation-induced mutations in minisatellite loci.
International Journal of Radiation Medicine, 1, 90-100.
Brown, J, Reading, S. J., Jones, S., Fitchett, C.
J., Howl, J., Martin, A., Longland, C. L., Michelangeli, F., Dubrova,
Y. E. and Brown, C. A. (2000) Critical evaluation of ECV304 as a human
endothelial cell model defined by genetic analysis and functional
responses: A comparison with the human bladder cancer cell line T24/83.
Laboratory Investigation. 80, 37-45.
Dubrova, Y. E., Plumb, M., Brown, J., Boulton, E.,
Goodhead, D. and Jeffreys, A. J. (2000) Induction of minisatellite
mutations in the mouse germline by low-dose chronic exposure to
-radiation and fission neutrons. Mutation Research, 453, 17-24.
Gibson, W., Bingle, L., Blendeman, W., Brown, J.,
Wood, J. and Stevens, J. (2000) Structure and sequence variation of the
trypanosome spliced leader transcript. Molecular and Biochemical
Parasitology, 107, 269-277.
Dubrova, Y. E., Plumb, M., Brown, J., Boulton, E.,
Goodhead, D. and Jeffreys, A. J. (2001) Reply to the letter to the
editor. Mutation Research, 478, 209-210.
Brown, J. and Brown, C. A. (2003) Evaluation of
reactive blue 2 derivatives as selective antagonists for P2Y receptors.
Vascular Pharmacology, 39, 309-315.
D’Souza, V. K., Nelson, P. N., Brown, J. Y. and
Brown, C. A. (2006) Evaluation of P2Y receptor subtypes in human
endothelial cells. Poster at the Luxembourg Proteomics Conference
October 11th-14th.
Brown, C. A., Brown, J. Y. and
Coleman, M. D. (2007) How drug metabolism influences treatment
outcomes. Expert Opinion in Drug Metabolism & Toxicology, 3 (6):
913-915.
Chapters
Dubrova, Y. E., Brown, J., Nesterov, V. N., Krouchinsky, N. G.,
Ostapenko, V. A., Plumb, M., Bois, P. and Jeffreys, (1999)
Radiation-induced mutation at mammalian minisatellite loci.
Fundamentals for the Assessment of Risks from Environmental Radiation,
259-264. Kluwer Academic Publishers.
Brown, J., Brown, C. A., Martin, A., Langel, U. and
Howl, J. (2000) Peptide mimetics of receptor extracellular domains
modulate signal transduction by P2Y2 receptors. Peptides for the New
Millennium. 594-596. Kluwer Academic Publishers. (Invited speaker at
the 16th American Peptide Symposium).
Brown, J., Howl, J., Martin, A., Soomets, U.,
Langel, U. and Brown, C. (2001) Single amino-acid substitutions in a
mimetic tetradecapeptide agonist of the human P2Y2 receptor prevent
second messenger activation. Peptides 2000 - Proceedings of the 26th
European Peptide Symposium, 913-914, Ėditions EDK, Paris.