Recent Group Publications
2007, Mann AM, Tighe BJ, Tear analysis and lens?tear interactions: Part I.
Protein fingerprinting with microfluidic technology, Contact Lens and
Anterior Eye , 30(3), 163-173 , 1367-0484
2007, Li LY, Tighe BJ., Nonlinear analysis of static axisymmetric
deformation of the human cornea, Computational Materials Science , 38,
618-624, 0927-0256
2006, M. C. McCairn, M. D. Hughes, A. V. Hine and A. J. Sutherland , A
platform for both solid-phase peptide nucleic acid (PNA)-oligomer synthesis and
subsequent in situ detection and quantification of nucleic acid sequences,
Journal of Combinatorial Chemistry, 8, 639-642
2006, M. C. McCairn, M. D. Hughes, A. V. Hine and A. J. Sutherland ,
Solid-Phase PNA Synthesis and In Situ Scintillation Proximity Assay for the
Detection of PNA-DNA Hybridization, Journal of Combinatorial Chemistry, 8,
1-3, 1520-4766
Complete list of Group Publications
2001 - 2002 - 2003 - 2004 - 2005 - 2006 - 2007
Contact Lens Materials.
Tighe BJ.
In: Contact Lenses, 5th edn: Anthony J Phillips & Lynne Speedwell, Editors Butterworth-Heinemann pp 59-78.
Tear analysis and lens-tear interactions: Part I. Protein fingerprinting with microfluidic technology.
Mann AM, Tighe BJ.
Contact Lens and Anterior Eye 2007;30:163-173.
Nonlinear analysis of static axisymmetric deformation of the human cornea.
Li L-y, Tighe BJ.
Computational Materials Science 2007;38:618-624.
Numerical simulation of corneal transport processes.
Li L-y, Tighe BJ.
J Roy Soc Interface 2006;3:303-310.
The anisotropic material constitutive models for the human cornea.
Li L-y, Tighe BJ.
J Struct Biol 2006;153:223-230.
N-Vinyl Amides: The next generation of monomers for ophthalmic biomaterials.
Henley C, Tighe B.
Contact lens and Anterior Eye 2006;29:200-201.
Macromolecular entrapment and comfort enhancement: Understanding the mechanism.
Ross G, Tighe BJ.
Contact lens and Anterior Eye 2006;29:201.
Measurement of frictional characteristics of contact lenses.
Tighe BJ.
Contact lens and Anterior Eye 2006;29:201-202.
Structural aspects of the design of ocular drug delivery systems.
Mahomed A, Tighe BJ.
Contact lens and Anterior Eye 2006;29:202.
Microfluidic technology for routine tear analysis.
Mann A, Tighe B.
Contact lens and Anterior Eye 2006;29:202-203.
Properties of SPDA, a biocompatible material.
Campbell D, Tighe BJ.
Contact lens and Anterior Eye 2006;29:203.
Compositional dynamics of phospholipids in the tear film.
Campbell D, Griffiths G, Tighe BJ.
Acta Ophthalmologica Scandinavica 2006;84:(s239)86.
Cross infection and contact ophthalmic devices: clinical trials of a disposable ophthalmic barrier system.
Tighe BJ, Franklin VJ, Henley CE, Kerr J, Gee H, Wolffsohn J, Flanagan J.
Acta Ophthalmologica Scandinavica 2006;84:(s239)44.
Microfluidic technology for routine tear analysis.
Mann A, Tighe BJ.
Acta Ophthalmologica Scandinavica 2006;84:(s239)167.
Novel ocular lubricants based on polymer-phospholipid recombinants and hyaluronic acid.
Rasul N, Tighe BJ.
Acta Ophthalmologica Scandinavica 2006;84:(s239)43.
N-vinyl amides: a versatile family of monomers for ophthalmic biomaterials.
Henley CE, Tighe BJ.
Acta Ophthalmologica Scandinavica 2006;84:(s239)69.
Solutions, contact lenses and wear: then and now.
Franklin VJ, Tighe BJ.
Acta Ophthalmologica Scandinavica 2006;84:(s239)40.
Structural aspects of the design of ocular drug delivery systems.
Mahomed A, Tighe BJ.
Acta Ophthalmologica Scandinavica 2006;84:(s239)181.
Towards a synthetic OOKP support frame.
Viitala R, Franklin VJ, Tighe BJ, Liu C, Lloyd AW.
Acta Ophthalmologica Scandinavica 2006;84:(s239)176.
Towards the development of purpose-designed ocular bandage lenses.
Bateman S, Mann A, Tighe BJ.
Acta Ophthalmologica Scandinavica 2006;84:(s239)155.
Centrifugally spun polyhydroxybutyrate fibres: accelerated hydrolytic degradation studies.
Foster LJR, Tighe BJ.
Polymer Degradation and Stability 2005;87:1-10.
A smart hydrogel-based system for controlled drug release.
Puyamoonwongsa P, Tighe BJ.
Chiang Mai J Sci 2005;32:471-478.
The Osteo-Odonto-Keratoprosthesis (OOKP).
Liu CSC, Paul B, Tandon R, Lee E, Fong K, Mavrikakis I, Herold J, Thorp S, Brittain P, Francis I, Ferrett C, Hull C, Lloyd AW, Green D, Franklin VJ, Tighe BJ, Fukuda M, Hamada S.
Seminars in Opthalmology 2005;20:113-128.
Presence of IgE antibody and kinin components in atopic and non-atopic contact lens wearing patients.
Mann AM, Tighe BJ.
Ophthalmic Res 2005;37:(S1):139. ISSN 0030-3747
The nature and fate of tear lipids in contact lens wear.
Mann AM, Campbell D, Griffith G, Tighe B.
Ophthalmic Res 2005;37:(S1):26&160. ISSN 0030-3747
Frictional and lubricity changes in contact lenses during wear.
Mahomed A, Nasso M, Tighe BJ.
Ophthalmic Res 2005;37:(S1):27&161. ISSN 0030-3747
Novel ophthalmic biomaterials.
Mahomed A, Henley C, Tighe BJ.
Ophthalmic Res 2005;37:(S1):27. ISSN 0030-3747
Silicone hydrogels: Trends in products and properties.
Ross G, Nasso M, Franklin V, Lydon F, Tighe BJ.
Ophthalmic Res 2005;37:(S1):27&162. ISSN 0030-3747
Selection and in vitro evaluation of a synthetic OOKP support frame.
Tighe BJ, Lloyd AW, Green D, Viitala R, Franklin VJ, Liu C.
Ophthalmic Res 2005;37:(S1):184. ISSN 0030-3747
Validity and repeatability of Goldmann applanation tonometry when used in conjuction with a prototype sterile barrier system.
Flanagan JG, Kerr J, Franklin V, Gee H, Tighe BJ.
Ophthalmol Vis Sci 2005;46:4869.
Silicone hydrogels: Structure, properties and behaviour.
Tighe BJ.
In: Silicone Hydrogels, 2nd edn: Continuous Wear Contact Lenses, D. Sweeney, Editor. Oxford, Butterworth-Heinemann 2004;pp 1-27.
Mathematical modelling of corneal swelling.
Li L-y, Tighe BJ, Ruberti JW.
Biomechanics and Modelling in Mechanobiology 2004;3:114-123.
Clinical and biochemical changes with silicone-hydrogel contact.
Santodomingo-Rubido J, Mann A, Wolffsohn J, Franklin V, Tighe B Gilmartin B.
Contact lens and Anterior Eye 2004;27:98-99.
The
development of a disposable ophthalmic barrier system to prevent
cross-infection from contact ophthalmic devices - an update.
Henley C, Franklin V, Tighe B, Kerr J, Gee H, Flanagan J.
Contact lens and Anterior Eye 2004;27:104.
Surface wettability of worn and unworn contact lenses.
Tighe BJ, Nasso M.
Ophthalmic Res 2004;36:(S1)34. ISSN 0030-3747
Ocular and dermal hydration: the role of hydrogels in the control of moisturisation.
Bahia R, Tighe BJ.
Ophthalmic Res 2004;36:(S1)66. ISSN 0030-3747
Therapeutic applications of contact lenses in myopia control.
Mahomed A, Punyamoonwongsa P, Tighe BJ.
Ophthalmic Res 2004;36:(S1)83. ISSN 0030-3747
Comparative physical and biochemical studies of silicone hydrogels contact lenses.
Franklin VJ, TigheBJ.
Ophthalmic Res 2004;36:(S1)35. ISSN 0030-3747
The
development of a disposable ophthalmic barrier system to prevent
cross-infection from contact ophthalmic devices - an update.
Franklin VJ, Henley C, Tighe BJ, Kerr J, Gee H, Flanagan J.
Ophthalmic Res 2004;36:(S1)69. ISSN 0030-3747
Novel composite materials for the fabrication of artificial corneae.
Lloyd A, Franklin V, Rose S, Morris C, Tighe B, Liu C.
Ophthalmic Res 2004;36:(S1)131. ISSN 0030-3747
The
application of capillary liquid chromatography mass spectrometry
techniques to the study of patient to patient variations in tear
chemistry.
Mann AM, Campbell D, Tighe BJ.
Ophthalmic Res 2004;36:(S1)34. ISSN 0030-3747
Contact lenses and comfort enhancers: in vivo and in vitro release of soluble PVA.
Mahomed A, Tighe BJ.
Ophthalmic Res 2004;36:(S1)34. ISSN 0030-3747
The application of lab-on-a-chip technology in tear composition, deposited protein and tear 'envelope' analysis.
Mann A, Tighe BJ.
Ophthalmic Res 2004;36:(S1)34. ISSN 0030-3747
A model for the preliminary biological screening of potential keratoprosthetic biomaterials.
Sandeman SR, Lloyd AW, Tighe BJ, Franklin V, Li J, Lydon F, Liu CSC, Mann DJ, James SE, Martin R.
Biomaterials 2003;24:4729-4739.
Silicone hydrogels: properties and performance.
Tighe B.
Contact Lens and Anterior Eye 2003;26:101.
Development of a biomimetic keratoprosthesis: ongoing developments.
Lydon F, Franklin V, Tighe B, Sandeman S, Lloyd A, Liu C.
Contact Lens and Anterior Eye 2003;26:209.
The
development of tear sampling and bioassay techniques for the study of
contact lens induced variations in tear protein profiles.
Mann A, Peach H, Tighe BJ.
Ophthalmic. Res, 2003;35:(S1)15.
Protein uptake study on Focus dailies and 1-Day Acuvue based on ex-vivo analysis of lenses from a 12hr clinical trial.
Franklin V, Purslow C, Tighe BJ, Wolffsohn JSW.
Ophthalmic Res 2003;35:(S1)16. ISSN 0030-3747
Frictional behaviour of contact lenses.
Bahia R, Tighe BJ.
Ophthalmic Res 2003;35:(S1)16. ISSN 0030-3747
Continuous and daily silicone hydrogel contact lens wear: biochemical markers.
Mann A, Santodomingo-Rubido J, Peach H, Franklin V, Wolffsohn JSW, Tighe BJ.
Ophthalmic Res 2003;35:(S1)16. ISSN 0030-3747
Formulating adhesive hydrogels for use as return electrodes during iontophoretic ocular drug delivery.
Mahomed A, Tighe BJ.
Ophthalmic Res 2003;35:(S1)20. ISSN 0030-3747
Hydrogel release systems in ocular and dermal drug delivery.
Mahomed A, Cartwright H, Tighe BJ.
Ophthalmic Res 2003;35:(S1)20. ISSN 0030-3747
Development of a biomimetic keratoprosthesis: Ongoing developments.
Tighe BJ, Lydon F, Franklin V, Sandeman S, Lloyd A, Liu CSC.
Ophthalmic Res 2003;35:(S1)21. ISSN 0030-3747
Disposable barriers for ophthalmic contact devices.
Tighe BJ, Kerr JM, Flanagan J, Franklin V, Gee HJ.
Ophthalmic Res 2003;35:(S1)257. ISSN 0030-3747
Soft lens materials.
Tighe BJ.
In: Contact Lens Practice, N. Efron, Editor. Oxford, Butterworth-Heinemann, 2002;pp 71-84.
Rigid lens materials.
Tighe BJ.
In: Contact Lens Practice, N. Efron, Editor. Oxford, Butterworth-Heinemann, 2002;pp 153-162.
The
application of counter immunoelectrophoresis in ocular protein studies:
Pt. I. Time dependent deposition patterns of immunoregulatory proteins
on anionic contact lenses.
Mann AM, Jones LW, Tighe BJ.
Contact Lens and Anterior Eye 2002;25:73-80.
The application of counter immunoelectrophoresis in ocular protein studies: Pt. II: Kinin activity in the lens-wearing eye.
Mann AM, Tighe BJ.
Contact Lens and Anterior Eye 2002;25:81-88 .
The detection of kinin activity in contact lens wear.
Mann AM, Tighe BJ.
Adv Exp Med Bio 2002;506:961-966.
Immunoblotting and tear sampling techniques for the study of contact lens-induced variations in tear protein profiles.
Peach HC, Mann AM, Tighe BJ.
Adv Exp Med Bio 2002;506:967-971.
Dynamic surface activity of biological fluids, ophthalmic solutions and nanostructures.
Tonge S, Rebeix V, Young R, Tighe B.
Adv Exp Med Bio 2002;506:593-599.
Polymers
for biodegradable medical devices XI. Microencapsulation studies:
characterization of hydrocortisone-loaded
poly-hydroxybutyrate-hydroxyvalerate microspheres.
Embleton JK, Tighe BJ.
J Microencapsulation 2002;19:737-752.
An investigation into kinin activity and immunoregulatory protein deposition in daily disposable lens wear.
Mann A, Wolffsohn J, Tighe B.
Contact Lens and Anterior Eye 2002;25:33-34. ISSN 1367-0484
Tear film nanostructures: implications for tear film stability.
Tonge S, Tighe B.
Contact Lens and Anterior Eye 2002;25:34. ISSN 1367-0484
Spoilation profiles of two extended wear hydrogel lenses.
Franklin V, Tighe B.
Contact lens and Anterior Eye 2002;25:34. ISSN 1367-0484
Tear lipid profiles on soft contact lenses.
Franklin V, Tighe B.
Contact lens and Anterior Eye 2002;25:34-35. ISSN 1367-0484
Frictional behaviour of contact lenses and ophthalmic solutions: measurement and clinical consequences.
Lydon F, Benning B, Young R, Tighe B.
Contact lens and Anterior Eye 2002;25:35. ISSN 1367-0484
Techniques for the study of physio-chemical properties of corneal tissue and synthetic hydrogel substitutes.
Lydon F, Tighe B, Young R.
Contact lens and Anterior Eye 2002;25:35-36. ISSN 1367-0484
The
development of immunoblotting and tear sampling techniques for the
study of contact lens induced variations in tear protein profiles.
Peach H, Mann A, Tighe B.
Contact lens and Anterior Eye 2002;25:42-43. ISSN 1367-0484
The potential of hydrogel contact lenses as delivery vehicles for therapeutic agents.
Tighe BJ, Cartwright H.
Ophthalmic Res 2002;34:(S1)25. ISSN 0030-3747
Silicone hydrogels: A comparative study of unworn and ex vivo lenses.
Franklin VJ, Lydon FJ, Tonge SR, Tighe BJ.
Ophthalmic Res 2002;34:(S1)32. ISSN 0030-3747
Towards a biomimetic hydrogel keratoprosthesis.
Franklin VJ, Lydon FJ, Li J, Tighe BJ, Sandeman S, Lloyd AW, Liu CS.
Ophthalmic Res 2002;34:(S1)37. ISSN 0030-3747
Predictive biochemical markers in ocular compatibility studies: kinin and vitronectin.
Tighe BJ, Mann AM, Franklin VJ.
Ophthalmic Res 2002;34:(S1)38. ISSN 0030-3747
Tear film clinical and biological effects of continuous contact lens wear.
Wolffsohn JS, Santodomingo-Rubido J, Mann A, Peach H, Franklin V, Tighe B, Gilmartin B.
Ophthalmic Res 2002;34:(S1)43. ISSN 0030-3747
Frictional behaviour of contact lenses: Measurement and consequences.
Tighe BJ.
Ophthalmic Res 2002;34:(S1)154. ISSN 0030-3747
Optimising novel materials for the fabrication of artificial corneae.
Lloyd AW, Lydon F, Franklin V, Sandeman S, Tighe BJ, Liu CS.
Ophthalmic Res 2002;34:(S1)177. ISSN 0030-3747
Biotribology of the lens-wearing eye.
Tighe B.
Contact Lens and Anterior Eye 2002;25:191.
Predictive biochemical markers in ocular compatibility studies: kinin and vitronectin.
Mann AM, Franklin VJ, Tighe BJ.
Contact Lens and Anterior Eye 2002;25:209.
Hydrogel release systems in ocular and dermal drug delivery.
Cartwright E, Tighe B.
Contact Lens and Anterior Eye 2002;25:209.
Silicone hydrogels: A comparative study of unworn and ex vivo lenses.
Tighe B, Tonge S, Franklin V, Lydon F.
Contact Lens and Anterior Eye 2002;25:210.
Towards a biomimetic hydrogel keratoprosthesis.
Tighe B, Lloyd A, Sandeman S, Lydon F, Franklin V.
Contact Lens and Anterior Eye 2002;25:210.
Tear film clinical and biological effects of continuous contact lens wear.
Santodomingo-Rubido J, Wolffsohn J, Mann A, Peach H, Tighe B.
Contact Lens and Anterior Eye 2002;25:210.
Centrifugally-spun polyhydroxybutyrate fibres: Effect of process solvent on structure, morphology and cell response.
Foster LJR, Davies SM, Tighe BJ.
J Biomater Sci Polymer Edn 2001;12:317-336.
Contact lens care, Part 3 - Contact lens materials and their interaction with tears.
Tighe BJ, Franklin VJ, Tonge SR.
Optician 5803 2001;221:22-29.
Contact lens care, Part 4 - Contact lens deposition, discoloration and spoilation mechanisms.
Franklin VJ, Tighe BJ, Tonge SR.
Optician 5808 2001;222:16-22.
Contact lens care, Part 5 - The design and development of wetting and multi-purpose solutions.
Tonge SR, Tighe BJ, Franklin VJ.
Optician 5812 2001;222:23-28.
Contact lens care, Part 6 - comfort drops, artificial tears and dry-eye therapies.
Tonge SR, Tighe BJ, Franklin VJ, Bright A.
Optician 5817 2001;222:29-34.
The ex vivo wettability of soft contact lenses.
Tonge SR, Jones L, Goodall S, Tighe BJ.
Curr Eye Res 2001;23:51-59.
Responsive hydrophobically associating polymers: a review of structure and properties.
Tonge SR, Tighe BJ.
Advanced Drug Delivery Reviews 2001;53:109-122.
Frictional behaviour of contact lenses.
Lydon F, Benning B, Tighe B.
Ophthalmic Res 2001;33:(S1)36. ISSN 0030-3747
Hydrogel release systems in ocular and dermal drug delivery.
Tighe B, Cartwright H, Atkins T.
Ophthalmic Res 2001;33:(S1)29. ISSN 0030-3747
Spoilation profiles of two extended wear hydrogel lenses.
Franklin VJ, Tighe BJ.
Ophthalmic Res 2001;33:(S1)35. ISSN 0030-3747
Bioevaluation of novel materials for the fabrication of artifical corneae.
Lloyd A, Lydon F, Franklin V, Li J, Tighe BJ, Sandeman S, Liu C.
Ophthalmic Res 2001;33:(S1)94. ISSN 0030-3747
Tear film nanostructures: implications for tear film stability.
Li J, Tonge S, Tighe BJ.
Ophthalmic Res 2001;33:(S1)41. ISSN 0030-3747
A novel approach to enhancing the mechanical properties of keratoprothestic materials.
Lydon F, Franklin V, Li J, Tighe B, Lloyd A, Sandeman S, Liu C.
Ophthalmic Res 2001;33:(S1)94. ISSN 0030-3747
Potential advantages of a synthetic osteo-odontal keratoprosthesis (OOKP).
Liu C, Green D, Hull C, Lydon F, Franklin V, Tighe B, Sandeman S, Lloyd A, Herold J.
Ophthalmic Res 2001;33:(S1)94. ISSN 0030-3747
An investigation into kinin activity and immunoregulatory protein deposition in daily disposable lens wear.
Tighe B, Mann A, Wolffsohn J.
Ophthalmic Res 2001;33:(S1)36.
Development of immunoblotting and tear sampling techniques to study contact lens induced variations in tear protein profiles.
Franklin V, Peach H, Mann A, Tighe BJ.
Ophthalmic Res 2001;33:(S1)36.
The detection of kinin activity in contact lens wear.
Mann AM, Tighe BJ.
Journal of Cornea and External Disease 2001;19:104.
Development of immunoblotting and tear sampling techniques to study contact lens induced variations in tear protein profiles.
Peach H, Mann A, Tighe BJ.
Journal of Cornea and External Disease 2001;19:113.
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