Medical projects are predominantly long term and run from concept to clinic.
These projects are underpinned by fundamental work to increase understanding of
the synthesis and behaviour of biocompatible and biomimetic polymers by:
- design and fabrication of new soft tissue analogues especially those related
to the cornea, intervertebral disc, articular cartilage and stratum corneum
(skin)
- collaboration with mathematical modellers to study poro-visco-elastic
behaviour of the human cornea
- synthesis and characterisation of analogues of biological fluids such as
tears, lung surfactant and synovial fluid to address dry-eye and related
diseases of lubricated biological interfaces
Non-clinical
projects include:
- novel polymeric materials that covalently incorporate quantum dots and
possess unique optical signatures
- new materials for biotechnology applications, such as high-throughput
synthesis, screening and purification of novel biologically relevant
molecules
- smart materials for generic application in the synthesis, assay and
deconvolution of combinatorial libraries;
- analytically-based investigation of plant-based molecular structures,
especially lipids and carbohydrates